Intrinsic Noise Profoundly Alters the Dynamics and Steady State of Morphogen-Controlled Bistable Genetic Switches.

During tissue development, patterns of gene expression determine the spatial arrangement of cell types.In many cases, gradients of secreted signalling molecules-morphogens-guide this process by controlling downstream transcriptional networks.A mechanism commonly used in these networks to convert the continuous information provided by the gradient i

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Peripheral Cystoid Degeneration Finding Using Intraoperative Optical Coherence Tomography in Rhegmatogenous Retinal Detachment

Koichi Nishitsuka, Katsuhiro Nishi, Hiroyuki Namba, Yutaka Kaneko, Hidetoshi Yamashita Department of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata, JapanCorrespondence: Koichi NishitsukaDepartment of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata City, Yamagata, JapanTel +

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Co-staining human PBMCs with fluorescent antibodies and antibody-oligonucleotide conjugates for cell sorting prior to single-cell CITE-Seq

Summary: The dual interrogation of the transcriptome and proteome with single-cell resolution provides exquisite insights into immune mechanisms in health and disease.Here, we describe a cutting-edge protocol wherein we Rollator combine Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-Seq), a technique utilizing antibody-oligonu

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